EIC Transition Challenge: RNA-based therapies and diagnostics for complex or rare genetic diseases

Last updated: 16.7.2025
Grant

The EIC Transition Challenge on RNA-based therapies and diagnostics is a unique funding opportunity designed to mature breakthrough technologies and innovative business ideas. It bridges the gap between laboratory proof-of-principle and clinical validation, aiming to bring novel RNA-based solutions for complex or rare genetic diseases closer to market. This program distinguishes itself by supporting both technological and commercial readiness, fostering the protection and exploitation of generated intellectual property.

Who is Funded: Eligible Applicants, Geographic Scope, and Objectives

The EIC Transition Challenge targets a broad range of applicants, from individual SMEs to research organizations and consortia, primarily within EU Member States and Associated Countries. The program's core objective is to advance RNA-based therapies and diagnostics, addressing unmet medical needs for complex or rare genetic diseases and driving their market readiness.

What is Funded: Project Types and Thematic Areas

This funding program focuses on critical health innovations, specifically RNA-based therapies and diagnostics, supporting projects from the lab to relevant application environments. The scope covers technology maturation and business case development, ensuring readiness for clinical validation and commercialisation.

Type and Scope of Funding

The EIC Transition Challenge provides grant funding for projects, with a specified range for financial support and a typical project duration, ensuring adequate time and resources for technology and business maturation.

Conditions and Requirements

Applicants must adhere to specific conditions regarding proposal submission, consortium composition, and intellectual property. Key regulatory documents and guidance are referenced to ensure compliance and successful project implementation.

Application Procedure

The application process for the EIC Transition Challenge involves detailed submission requirements and a structured evaluation to identify high-potential projects. Support is available for applicants throughout these stages, and successful proposals may receive a Seal of Excellence.

The EIC Transition Challenge is governed by a comprehensive set of legal and official documents stemming from the broader Horizon Europe framework, ensuring transparent and legitimate operation.

Similar Programs

#RNA-based therapies#genetic diseases#EIC Transition Challenge#diagnostics#rare diseases#Horizon Europe funding#medical innovation#biotechnology grants#technology maturation#business model development#clinical validation#SME funding#research organisations#consortia#EU grants#healthcare research#disruptive innovation#intellectual property#TRL advancement

Funding Overview

Funding Status

Funding Status:

Closed

Maximum Amount

Maximum Amount:

2,500,000 €

Allocated Budget

Allocated Budget:

Total for EIC Transition 2022: 131,360,126 € (for each of the four topics under the call)

Open Until

Open Until:

31.12.2027

Award Channel

Award Channel:

Framework Programme Call

Region

Region:

European Union, Associated Countries

Sectors

Sectors:

Healthcare, Medical Technology, Research and Development

Beneficiaries

Beneficiaries:

Biotechnology, Healthcare, Medical Technology, Research & Development

Application Type

Application Type:

Optional Consortium

Funding Stages

Funding Stages:

Applied Research, Experimental Development, Prototyping, Pilot Testing, Product Development, Commercialization, Market Introduction

Funding Provider

Program Level:

European Union

Funding Body:

European Commission

0 x 0
XS