Development of antibodies and antibody-derived proteins for the prevention and treatment of infectious diseases with epidemic potential

The program primarily targets a wide array of legal entities, including businesses, non-profit organizations, public sector bodies, and research institutions, emphasizing a broad international reach to tackle infectious diseases with epidemic potential. Geographically, it extends beyond the European Union and Associated Countries to include the United States and other regions significantly affected by target viruses, fostering a collaborative global response.

This program focuses on funding innovative health research and development, specifically targeting the creation of new antibody-based treatments for infectious diseases with epidemic potential. Projects must concentrate on existing therapeutic candidates and span from preclinical validation through to initial human clinical safety studies. Funding covers eligible costs determined via a lump sum approach.

This Horizon Europe grant provides substantial financial support for developing antibody-based therapeutics, utilizing a simplified lump sum grant model. Each successful project is expected to receive a significant fixed amount, emphasizing the delivery of concrete research outcomes. While specific project durations are not fixed, the focus on clinical studies implies multi-year timelines.

Applicants and beneficiaries must adhere to comprehensive conditions covering application admissibility, collaboration requirements, and specific regulations like the exclusion of high-risk suppliers in communication networks. Key financial conditions include the lump sum funding model, requiring detailed budget estimations and justification. Additionally, proposals must integrate ethical considerations, data management, and the use of specific European satellite services, ensuring a responsible and impactful research approach.

The application process for this program is a single-stage submission, requiring applicants to use specific forms and adhere to outlined evaluation criteria. Proposals are assessed based on their excellence, impact, and implementation, with clear thresholds for success.

The program is fundamentally governed by the Horizon Europe Framework Programme and its specific program decision, alongside the EU Financial Regulation. Operational details and procedures are further defined in a comprehensive set of Work Programme General Annexes and specific decisions related to funding mechanisms like lump sum contributions. All key legal and official texts are accessible via the European Commission's Funding & Tenders Portal and Eur-Lex.